After investigating 315 dietary supplements, the results showed that most of them did not produce weight loss.
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For this study, the researchers completed a comprehensive review of 315 existing clinical trials of weight-loss supplements and therapies. Most studies show that these supplements are in use Among them, no weight loss effect was produced.
The corresponding author, Dr. John Butts, associate professor of the Department of Geriatrics at the University of North Carolina (UNC) School of Medicine, said: “Our findings are important to clinicians, researchers and industry because they show Strict evaluation of weight loss products is required. Only in this way can we provide clinicians with accurate data and provide our patients with opinions and suggestions with higher certainty.”
The author of the paper explained that patients often struggle to lose weight or maintain weight, either because the existing Federal Drug Administration (FDA) approved therapies lack efficacy, or they are unable to obtain obesity Medical specialist treating. Although the Office of Dietary Supplements of the National Institutes of Health has promoted the scientific development of dietary supplements by evaluating information, stimulating, and supporting research, members of the TOS believe that non-FDA therapies should be evaluated and qualitatively integrated to provide scientific evidence. It is very important to guide its members.
Researchers focused on 315 peer-reviewed randomized controlled trials and analyzed them for risk of bias. As a result, 52 studies were classified as studies with low risk of bias and sufficient to support efficacy. Among them, 16 studies showed that compared with placebo, there was a significant pre/post difference in body weight between groups. In these studies with different methods, the weight loss ranged from 0.3 to 4.93 kg.