2021-11-23

New research reveals that aspirin may increase the risk of heart failure by 26%

By yqqlm yqqlm

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dcdf46259e1586c - New research reveals that aspirin may increase the risk of heart failure by 26%

there has been great controversy about the effect between aspirin and heart failure

the purpose of this new study is to evaluate the relationship between the drug and the incidence of heart failure in people with / without heart disease, so as to evaluate whether the drug is related to the diagnosis of heart failure in high-risk groups</ P>

‘s so-called “risk” refers to one or more factors, including smoking, obesity, hypertension, high cholesterol, diabetes and cardiovascular diseases. p>

New research reveals that aspirin may increase the risk of heart failure by 26%

study diagram – 1: risk relationship over time

participants were all aged 40 and over, and did not step on the baseline of heart failure at the beginning. Then the researchers began to try to record the physical conditions of the two groups of participants (incidence of fatal / nonfatal heart rate failure requiring first hospitalization).

in addition, the average age of participants was 67 years, with 34% of women. At baseline, there were 25% of participants (7698) Aspirin was taken. During the 5.3 years of follow-up, 1330 participants were found to have heart failure.

assessed gender, age, body mass index, smoking, drinking, blood pressure, heart rate, blood cholesterol, creatinine, hypertension, diabetes, cardiovascular disease, renin therapy, renin angiotensin aldosterone system inhibitor therapy, calcium channel blockers, and so on. Diuretics β- After factors such as blockers and lipid-lowering drugs, the researchers finally determined that aspirin was associated with a 26% increase in the risk of newly diagnosed heart failure.

7a0f9dd3ee842fb - New research reveals that aspirin may increase the risk of heart failure by 26%

study diagram – 2: systolic / diastolic blood pressure

in stratified analysis, in order to test whether the results show a After matching the heart failure risk factors of aspirin users / non users, the researchers further excluded patients with a history of cardiovascular disease and repeated the analysis.

the final finding was 74% (22690) Among participants without cardiovascular disease, aspirin use was associated with a 27% risk of heart failure. Before that, they had noticed that patients at such risk should take aspirin carefully.

mujaj commented that aspirin was a very common common drug in his study, and about 1 / 4 of the participants took aspirin. They calculated the follow-up A large randomized trial covering many countries is planned to further verify this conclusion