Scientists have developed new biomaterials to repair the heart, muscles and vocal cords
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“People who recover from heart injury often face a long and difficult journey. Healing is challenging because the tissue must withstand continuous movement when the heart beats. The same is true for the vocal cords.” Bao Guangyu, a doctoral student in the Department of mechanical engineering at McGill University, said: “so far, there is not enough powerful injection material to complete this work.”
developed a new injectable hydrogel for wound repair by the team led by Professor Luc Mongeau and Professor Li Jianyu. This hydrogel is a biomaterial that provides cells with room for survival and growth. Once injected into the body, the biomaterial forms a Stable porous structure allows live cells to grow or pass to repair damaged organs.
Bao Guangyu said: “the results are promising. We hope that one day this new hydrogel will be used as an implant to restore the voice of the injured vocal cord, such as the survival of laryngeal cancer.”
scientists tested the durability of their hydrogels in the machine they developed to simulate human vocal cord extreme biomechanics. They vibrated more than 6 million times at a rate of 120 times per second, and new biomaterials remained intact, while other standard hydrogels were broken into fragments.
is “incredible.” we can’t believe that it works perfectly in our tests. Before our work, there is no injectable hydrogel with high porosity and toughness. To solve this problem, we introduced a pore forming polymer in the formula. Bao Guangyu said.
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scientists say that this innovation has opened up new ways for other applications, such as drug delivery, tissue engineering and modeling of drug screening. The team even hopes to use hydrogel technology to create artificial lung to test COVID-19 drugs. /p>
Professor Li Jianyu, chairman of biomaterials and musculoskeletal health research in Canada, said: “our work highlights the synergy of materials science, mechanical engineering and bioengineering in creating new biomaterials with unprecedented performance. We look forward to transforming them into clinical applications.”